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What does it mean if the genus match is "low"?

Date added:
Thursday, 05 February 2009

Answer

A low match shows that the DNA sequence isolated from the organism does not closely match any sequences in the NCBI database.  If the DNA isolated is a clean sequence then it is likely that the organism present is a novel organism (i.e. not in the database). Another cause of a low match is that the DNA isolated from the sample may contain a lot of “noise” and therefore not provide a clean sequence. As such, a low similarity ratio should be interpreted with caution.

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